MEDICINAL
INSIGHTS
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DOCTORS
At Naativv Bioscience, we believe in scientific evidence as the way to advance our understanding of cannabis’ therapeutic properties and its wide range of applications. To support this, we aim to be an educational hub for doctors and health practitioners who seek a better understanding of medicinal cannabis.
Our Research Library is the first part of this initiative, a dedicated portal where scientific research, studies, and clinical trial results past and present are available on-demand and indexed for ease of reference. The second, our Scientific and Medical Advisory Board, is our proactive effort to facilitate learning and promote discourse within the medical fraternity.
Both our Library and Board are scheduled for launch in Q4 2021.
PATIENTS
Cannabis as a medicine has been used for thousands of years in all corners of the globe. It is only in recent times, with the progress of scientific research, that this complex plant is finally seeing mainstream medical use.
It confirms what we already know: that cannabis is naturally-sourced, sustainable, and affordable for an exceptionally broad range of conditions. Medicinal cannabis is a safe and natural alternative treatment for such conditions as chronic pain and nausea that afflict large proportions of the world’s population, and who often are treated with opioid-based pharmaceutical drugs. Presently, medicinal cannabis products are accessible in North America, in most European countries, and now New Zealand.
Widely established indications include:
• Nausea and vomiting due to chemotherapy
• Seizures and pain due to multiple sclerosis, epilepsy, and similar neurological disorders
Indications being researched:
• Cancer treatment
• Chronic pain
• Developmental disorders and many more
As a patient-focused organization, Naativv Bioscience is committed to increasing prescribed access to this high-quality, high efficacy medicine to members of our society in need of aid and relief.
THE
ENDOCANNABINOID SYSTEM
After discovering tetrahydrocannabinol (THC) and cannabidiol (CBD) in the cannabis plant, researchers questioned how these molecules affected the human body, leading them to a critical breakthrough: the revelation of a vast network of cellular receptors known as the endocannabinoid system (ECS).
This revolutionary discovery not only identified how cannabinoids work; it also revealed a sophisticated physiological system that helps the body maintain its internal state of equilibrium, known as homeostasis.
PHYTOCANNABINOIDS
Phytocannabinoids, or exogenous cannabinoids, are plant-derived cannabinoids produced by glandular trichomes covering the surface of the cannabis plant, especially its flowers. Containing more than 120 different types of phytocannabinoids, the most abundant are tetrahydrocannabinol (THC) and cannabidiol (CBD).
THC is the psychoactive compound that creates the feeling of being high. What is less reported are the many health benefits of THC; it has been shown to potentially help increase the appetite in eating disorder patients, inhibit neurodegenerative disease, and treat severe sickness in cancer patients.
CBD is the second most prevalent active ingredient in cannabis, yet comes without THC’s psychoactive effects. Its medicinal use has shown life-changing results in patients suffering from a variety of debilitating health conditions such as anxiety, insomnia, and chronic pain.
Studies are currently underway on other minor phytocannabinoids like GBG, CBN, CBC, THCA, and CBDA, to uncover their therapeutic potential.
ENTOURAGE EFFECT
A well-supported theory is the entourage effect, a proposed modality where all cannabis compounds are taken together rather than individually thus enabling them to act synergistically for increased therapeutic benefit. The four main cannabis compounds are phytocannabinoids, terpenes, flavonoids, and lipids (waxes).
Beyond the 120 different phytocannabinoids, there are numerous terpenes which are essential aromatic oils that vary between different strains of cannabis plant. Some of these have known pharmacological effects and have been studied.
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